
Two methods are described that are suitable for the rapid screening of compounds as urease inhibitors. The first utilizes an electrode sensitive to NH4+ ions; the second is dependent on pH rise. A feature of both is a direct readout of reaction rate.
Acetazolamide, Pyelonephritis, Drug Evaluation, Preclinical, Humans, Proteus vulgaris, Hydrogen-Ion Concentration, Hydroxamic Acids, Urease, Anti-Bacterial Agents
Acetazolamide, Pyelonephritis, Drug Evaluation, Preclinical, Humans, Proteus vulgaris, Hydrogen-Ion Concentration, Hydroxamic Acids, Urease, Anti-Bacterial Agents
| citations The total number of citations received by all articles of the researcher of interest. | 51 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
