"Chronic urticaria.One French out of 5 will suffer from urticaria at least once in his life, but only in 10% of the cases will chronic urticaria occur. Physicians must know its main characteristics: hives and angioedema lasting less than 24h and 72h, respectively. Any discrepancy with this definition must lead physicians to refer to specialists in order to consider differential diagnoses. Physicians must explain to patients that chronic urticaria is not allergic, but can be induced by physical stimulus (friction, cold contact, etc.), and that extensive explorations are not mandatory. However physicians must pay attention to the poor quality of life of these patients. A several-steps management will be proposed, according to the 2019 French guidelines on chronic urticaria, which are available on line: 2nd generation anti-H1 antihistamines, possibly up-dosed, and ultimately, patients can be referred for step 3 treatment with biotherapy or immunosuppressive molecules."