[Glioma Cell Biology].

Kensuke, Tateishi

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Article . 2021

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[Glioma Cell Biology].

descriptionPublicationkeyboard_double_arrow_right Article 08 Jun 2021 Japanese Journal:No shinkei geka. Neurological surgery, volume 49 (issn: 0301-2603,

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Authors: Kensuke, Tateishi;

pmid: 34092552

[Glioma Cell Biology].

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Abstract

In this review, I summarized the biology of gliomas. Through past clinical and basic studies, I reviewed the evidence of the cell of origin of gliomas and the presence of brain tumor-initiating cells in gliomas, which are driven by multiple genomic alterations. In addition, the complicated tumor heterogeneity and neuronal-glioma network were studied. These mechanisms may underlie the treatment resistance and poor prognosis and support the identification of novel therapeutic targets for gliomas.

Related Organizations

Yokohama City University
Japan

Keywords

Brain Neoplasms, Humans, Glioma

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