Apitherapy - applying the Bee venom to treat medical condition is ancient. According to analysis of google searches, over the past decade there was a steady increase in interest regarding apitherapy. There are some controlled studies alluding to its beneficial effects. There are several anti-inflammatory peptides in the venom, i.e. Melittin, Apamin and more. There are efforts to synthesize them and apply them for therapy. Caution is needed to avoid allergy to bee venom as well as to an anaphylactic shock.