Emergence of ST15 Klebsiella pneumoniae Clinical Isolates Producing Plasmids-Mediated RmtF and OXA-232 in China.
Copyright policy )Emergence of ST15 Klebsiella pneumoniae Clinical Isolates Producing Plasmids-Mediated RmtF and OXA-232 in China.
RmtF, as 16S rRNA methyltransferase, leads to high-level resistance to aminoglycoside and is now barely reported.Three rmtF-positive Klebsiella pneumoniae isolates, belonging to the pandemic clone sequence type 15, were isolated from children and coproduced bla OXA-232 and bla CTX-M-15. The rmtF gene was located on an IncFIB transformable plasmid of 128,536-bp and bla OXA-232 was on a 6141-bp ColKP3 plasmid, respectively.Plasmids with rmtF found worldwide, shared relatively low similarity, and merely matched partly in their multidrug resistance region. Notably, clinical isolates coproducing rmtF and bla OXA-232 are gradually increasing in China.
- Fudan University China (People's Republic of)
- Second Affiliated Hospital of Zhejiang University China (People's Republic of)
- Huashan Hospital China (People's Republic of)
klebsiella pneumoniae, rmtf, blaoxa-232, Infection and Drug Resistance, st15, Short Report, amonoglycoside, Infectious and parasitic diseases, RC109-216
klebsiella pneumoniae, rmtf, blaoxa-232, Infection and Drug Resistance, st15, Short Report, amonoglycoside, Infectious and parasitic diseases, RC109-216
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