
Kod 47 radnika drvne industrije sprovedena su ispitivanja u cilju procene senzibilizacije sa specifičnim alergenima i ventilatorne funkcije. Svim ispitivanim osobama popunjavan je MRC upitnik za respiratornu simptomatologiju, određivan je akutni i hronični efekt drvne prašine na ventilatornu funkciju (na njene pojedine parametre) izvršeno je intradermalno testiranje sa pet specifičnih alergena drvne industrije i određivan je nivo serumskih IgG, M i A. Ispitivanja su pokazala senzibilizaciju na specifične alergene kod 55,3% radnika intradermalnim testiranjem. Kod radnika sa pozitivnim intradermalnim testovima registrovan je i akutan i hroničan efekt drvne prašine na parametar FEF75-85% od FVK-a. Ovo ukazuje na eventualni mogući konstriktorni efekat drvne prašine, pretežno lokaliziran u malim disajnim putevima kod senzibiliziranih osoba.
Ventilatory functions and skin hypersensitivity to allergens present in the wood industry were assessed in 47 workers with an average exposure of 12.8 years. On the basis of the MRC questionnaire for respiratory symptoms, each worker was submitted to the measurements of ventilatory lung function parameters for acute and chronic effects of exposure. Intradermal testing with five specific dust allergens was performed, and the level of serum immunoglobulins was determined. Fifty-five per cent of the workers were found to be hypersensitive to specific allergens. In those with positive skin tests, acute and chronic effects of wood dust on FEF75-85% and PVC were noted, which points to a possible constrictive effect of wood dust localized mostly in the small airways in sensitized persons.
Lung Diseases, Male, Occupational Diseases, Hypersensitivity, Humans, Middle Aged, Lung Volume Measurements, Wood, Skin Tests
Lung Diseases, Male, Occupational Diseases, Hypersensitivity, Humans, Middle Aged, Lung Volume Measurements, Wood, Skin Tests
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