Rehabilitation ifluences of adaptive physical exercises are based on interrelation of impellent and also vegetative and muscular functions. In particular at corrective picked up physical exercises according to functionalities of an organism muscular and vegetative system causes positive changes in work of internal bodies. The purpose of our experiment was to study the role of physical exertion in the process of comparative restoration of impaired homeostasis of individuals with limited abilities (Down syndrome), along with drug therapies; establishing the form and power of physical impact. Received data of researching and control group, allows conclude, that the complex adaptive exercises and correct by selected power of physical load, with the accounting of time, causes comparative rehabilitation of muscular and vegetative systems for people with congenital aberration of genes, which is very important for their vital activity, from our point of view.