
An interaction between thiamine hydrochloride and DL-alpha-lipoic acid in aqueous solution was depicted. Evidence is presented through spectrophotometric as well as vapour pressure measurements to show that thiamine hydrochloride and DL-alpha-lipoic acid form a single 1:1 complex. The stability constant and the molar extinction coefficient of the complex (at 244 nm) were determined at 25 degrees C and found to be 3.1-10(4) and 970, respectively. Vapour pressure measurements at 60 degrees C reveal that more or less complete dissociation of the complete takes place at this temperature.
Solutions, Thioctic Acid, Temperature, Spectrophotometry, Ultraviolet, Thiamine, Volatilization
Solutions, Thioctic Acid, Temperature, Spectrophotometry, Ultraviolet, Thiamine, Volatilization
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