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Investigation of Orthohantavirus Seroprevalence in Northern Rural Areas of Denizli Province, Turkey.

Authors: Polat, C.; Ergin, Çağrı; Akkaya, Y.; Oktem, I.M.A.;

Investigation of Orthohantavirus Seroprevalence in Northern Rural Areas of Denizli Province, Turkey.

Abstract

Orthohantaviruses infect humans via inhalation of the viral particles in the excreta of infected rodents or direct contact with infected rodents. The infections caused by Puumala orthohantavirus (PUUV) and Dobrava-Belgrade orthohantavirus (DOBV) have been reported in Turkey. Serum samples of 346 healthy volunteers who are in the high-risk group of Orthohantavirus infections among the residents of Çal, Baklan, Çivril, and Bekilli counties, located in the northeast part of Denizli province, were used in this study. The samples were screened and confirmed using commercial ELISA and immunoblot tests, which detect IgG antibodies against DOBV, PUUV, and Hantaan orthohantavirus. IgG antibodies against PUUV were detected in the samples of 2 volunteers (2/346, 0.6%). One was a veterinarian and the other a farmer and they live in the Baklan and Çal counties, respectively. Both of them have a high probability of exposure to the virus, based on their occupation and living conditions. However, no symptoms were found in the clinical findings of both cases. This study is the first publication of reported PUUV seropositivities from the southwestern part of Turkey.

Keywords

Male, Orthohantavirus, Turkey, very elderly, environmental exposure, Antibodies, Viral, Puumala virus, human experiment, immunoglobulin G, Seroepidemiologic Studies, health care management, Aged, 80 and over, seroprevalence, Geography, animal hunting, adult, Middle Aged, aged, Dobrava virus, female, blood sampling, Female, immunoblotting, nucleocapsid protein, Hantavirus, Adult, 570, Adolescent, Hantavirus Infections, Article, agricultural worker, Young Adult, male, 616, geographic distribution, Humans, controlled study, human, normal human, veterinarian, Aged, high risk population, Hantavirus infection, daily life activity, enzyme linked immunosorbent assay, adolescent, Immunoglobulin G

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Top 10%
Average
Average
Green
gold