Response of Lichen Planopilaris to Pioglitazone Hydrochloride
Copyright policy )Response of Lichen Planopilaris to Pioglitazone Hydrochloride
Lichen planopilaris (LPP) is a cicatricial alopecia that often causes permanent hair loss. Pioglitazone, a peroxisome proliferator activated receptor-gamma (PPAR- γ) agonist, has demonstrated immunomodulatory properties that may offer an effective treatment modality. This retrospective analysis describes 23 patients with LPP treated with adjunctive pioglitazone. Most (18/25) demonstrated significant reduction in patient-reported symptoms and clinical signs of inflammation. No adverse effects were reported. J Drugs Dermatol. 2019;18(12):1276-1279.
Adult, Male, Pioglitazone, Lichen Planus, Middle Aged, PPAR gamma, Treatment Outcome, Humans, Immunologic Factors, Female, Aged, Retrospective Studies
Adult, Male, Pioglitazone, Lichen Planus, Middle Aged, PPAR gamma, Treatment Outcome, Humans, Immunologic Factors, Female, Aged, Retrospective Studies
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