Skin penetration of CoQ10 in the rat.

L, Giovannini; A A, Bertelli; V, Scalori; L, Dell'Osso; M G, Alessandrì; M, Mian

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Article . 1988

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Skin penetration of CoQ10 in the rat.

descriptionPublicationkeyboard_double_arrow_right Article 20 Dec 1988 English Journal:International journal of tissue reactions, volume 10 (issn: 0250-0868,

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Authors: L, Giovannini; A A, Bertelli; V, Scalori; L, Dell'Osso; M G, Alessandrì; M, Mian;

pmid: 3182185

Skin penetration of CoQ10 in the rat.

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Abstract

Skin penetration of coenzyme Q10 (CoQ10) was investigated after topical treatment in the rat. The drug was suspended in olive oil and administered at two different concentrations. Coenzyme levels were found to be directly related to the concentrations employed and the contact time. CoQ10 topical treatment might therefore be proposed as a good pharmacological tool in dermatology and cosmetology.

Related Organizations

University of Pisa
Italy

Keywords

Male, Time Factors, Ubiquinone, Administration, Topical, Osmolar Concentration, Coenzymes, Rats, Inbred Strains, Absorption, Rats, Animals, Skin

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