Benign glandular enlargement of male breast is called gynaecomastia.Various drugs have been implicated as the cause. Most widely used HAART regimen TLE is enlisted in least common cause of gynaecomastia. A 42 yr old male diagnosed HIV seropositive since last 10 yrs was put on TLE regimen and he presented with gynaecomastia since 11 months. We hereby report this finding on HAART.