OCTA expands the spectrum of multimodal retinal imaging as a non-invasive procedure. Subtraction analysis of two temporally dense and identical B-scan images only show changes corresponding to the flow in the blood vessels. Freely selectable segmentation visualization of different layers of the retina, RPE, choriocapillars and choroid. By means of manufacturer-specific quantification options and 3-D representation changes in findings under a therapy can be well represented. At present, OCTA is still bound to a corresponding B-scan. The OCTA is currently not a substitute for the conventional FAG, as it can give no indication of permeability disorders and fluid movements over time and the image is still very limited. These limitations will soon disappear as a result of rapid technological development and provide the OCTA with a permanent place in the multimodal imaging of the retina. With further development, new biomarkers for therapy and re-treatment may be safely defined for some diseases.