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Chalone-like inhibition of DNA synthesis in helminths.

Authors: K, Kudrna; J, Prokopic;

Chalone-like inhibition of DNA synthesis in helminths.

Abstract

Chalone-like inhibitory activity was found in extracts from tissues of Taenia crassiceps cysticercus and tissues of adult Ascaris suum. The inhibitory effects were partially species nonspecific: The extracts from T. crassiceps larvae inhibit both T. crassiceps and Mesocestoides corti larvae DNA synthesis. Extracts from A. suum, however, inhibit only T. crassiceps. Besides them, the inhibitory factor from mouse brain inhibits both T. crassiceps and M. corti DNA synthesis. When the inhibitory factor from A. suum was applied 4 times during 24-hr culture (at 6-hr intervals), the inhibitory effect was decreased.

Keywords

Brain Chemistry, Taenia, Tissue Extracts, Ascaris, DNA, Growth Inhibitors, Mice, Depression, Chemical, Larva, Animals, Cestoda

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
gold