[Cholinergic effects of nootropics].
Copyright policy )[Cholinergic effects of nootropics].
With respect to the enhancing effect of nootropics on learning and memory, the influence of some of these drugs on the high affinity choline uptake has been investigated. Meclofenoxate competes with choline uptake in vitro because of its similar side chain; other nootropics are without in vitro effects. A single dose of pramiracetam enhances the choline uptake in cortex and hippocampus. Application of meclofenoxate decreases the uptake of choline. Other nootropics lack acute effects. Possible increases of uptake after repeated dosage disappear within 24 h.
Brain, Rats, Inbred Strains, Piracetam, Choline, Rats, Meclofenoxate, Memory, Reference Values, Animals, Learning, Female, Pyrithioxin, Central Nervous System Agents
Brain, Rats, Inbred Strains, Piracetam, Choline, Rats, Meclofenoxate, Memory, Reference Values, Animals, Learning, Female, Pyrithioxin, Central Nervous System Agents
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).8 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!