Mesenchymal stem cells and IL-37: a powerful combination.
Copyright policy )Mesenchymal stem cells and IL-37: a powerful combination.
Mesenchymal stem cells (MSCs) are able to exert immunomodulatory and anti-inflammatory actions. Thanks to these properties, MSCs may be a promising alternative approach for the treatment of inflammatory disease. Important cytokines involved in inflammation are those included in the IL-1 family. Interleukin-37 (IL-37) is one of the member able to suppress both innate and adaptive immunity. Recently, it was found that MSCs and their derivatives can modulate IL-37, and MSCs expressing IL-37 seem to have an enhanced therapeutic efficacy.
IL-37; Inflammation; Mesenchymal stem cells;, Inflammation, mesenchymal stem cells, Mesenchymal Stem Cells, Mesenchymal Stem Cell Transplantation, IL-37, inflammation, Cytokines, Humans, Interleukin-1
IL-37; Inflammation; Mesenchymal stem cells;, Inflammation, mesenchymal stem cells, Mesenchymal Stem Cells, Mesenchymal Stem Cell Transplantation, IL-37, inflammation, Cytokines, Humans, Interleukin-1
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