The Postthrombotic Syndrome Abstract. The postthrombotic syndrome is defined by clinical signs (objectively assessed findings) and complaints that occur after a deep vein thrombosis. The most commonly used score is the Villalta score, but the most easily applicable is the Ginsberg score (pain, swelling > 1 month). Unfortunately, the current scores are not specific in this respect and are used differently in the different studies. The natural course of deep vein thrombosis during anticoagulation and the occurrence of a postthrombotic syndrome are important predictors of the long-term outcome. Four large controlled studies examined the effect of compression stockings on the development of a postthrombotic syndrome, they are summarized and discussed in this paper. Whether compression stocking do or do not prevent a postthrombotoc syndrome is questioned. Duplex sonographic findings such as residual thrombusload and postthrombotic venous reflux are unfortunately not predictive for the development of a postthrombotic syndrome, as shown in a prospective study.