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Article . 1986

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[Mediated action of phytogenic antineoplastic agents on rats with Pliss lymphosarcoma].

descriptionPublicationkeyboard_double_arrow_right Article 19 Nov 1986 Russian Journal:Eksperimental'naia onkologiia, volume 8 (issn: 0204-3564,

Authors: K D, Rakhimov; O K, Kabiev; A K, Kuralasov; Z I, Togaĭbaeva; S M, Vermenichev;

pmid: 3093186

[Mediated action of phytogenic antineoplastic agents on rats with Pliss lymphosarcoma].

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Abstract

The action of drugs of plant origin and of alkylating compounds (sarcolysine, prospidin) was accompanied by hormonal changes in rats with inoculated Pliss' lymphosarcoma. After the use of polyphenol plant drugs the secretion of pituitary FSH was inhibited, the blood concentration of testosterone was reduced and the cortisol secretion was substantially increased. The alkylating compounds stimulated the production of FSH, increased the secretion of testosterone, and clearly lowered the cortisol level.

Keywords

Flavonoids, Hydrocortisone, Polymers, Lymphoma, Non-Hodgkin, Polyphenols, Antineoplastic Agents, Phytogenic, Rats, Mice, Phenols, Pituitary Gland, Animals, Testosterone, Follicle Stimulating Hormone

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