[Abnormal localization of proto-oncogene c-ets 1 in acute leukemia with translocation t(1: 11)(q21: q23)].

J F, Caubet; A, Gegonne; D, Stéhelin; R, Berger

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Comptes Rendus de l Académie des Sciences - Series III - Sciences de la Vie

Article . 1986

Data sources: Europe PubMed Central

[Abnormal localization of proto-oncogene c-ets 1 in acute leukemia with translocation t(1: 11)(q21: q23)].

descriptionPublicationkeyboard_double_arrow_right Article 15 Oct 1986 French Journal:Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, volume 302 (issn: 0764-4469,

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Authors: J F, Caubet; A, Gegonne; D, Stéhelin; R, Berger;

pmid: 3091200

[Abnormal localization of proto-oncogene c-ets 1 in acute leukemia with translocation t(1: 11)(q21: q23)].

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Abstract

The chromosome localization of a 5.4 kb DNA genomic probe of proto-oncogene c-ets 1 has been analysed in an acute monocytic leukemia with t (1; 11) (q21; q23) translocation. The c-ets probe has been translocated onto the rearranged chromosome 1, suggesting the involvement of the proto-oncogene in leukemias with chromosome rearrangements at band 11 q23.

Keywords

Karyotyping, Leukemia, Monocytic, Acute, Proto-Oncogenes, Chromosomes, Human, 1-3, Chromosome Mapping, Humans, Infant, Female, Proto-Oncogene Mas, Translocation, Genetic

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