Interpretation of Arterial Blood Gas Analysis Abstract. Arterial blood gas test is a common diagnostic method in clinical practice. It can detect the presence and identify the causes of acid-base and oxygenation disturbances. The correct interpretation of the results begins with a careful clinical evaluation of the patient and the knowledge of the basic principles of acid-base regulation. A systematic stepwise approach is recommended to find an accurate diagnosis and to better identify mixed acid-base disorders. Here, a possible approach according to the physiological model is presented.