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[A three-cycle mechanism of the respiratory chain].

Authors: V P, Skulachev;

[A three-cycle mechanism of the respiratory chain].

Abstract

A scheme of the respiratory chain is presented, according to which three delta mu H-generators (complexes I, III and IV) provide for the transmembrane transport of ten H+ ions per atom of adsorbed O2. It is assumed that all the three delta mu H-generators operate in accordance with the same mechanism, namely, they translocate electrons at a distance averaging 1/2 of membrane width, whereas protons moving in the opposite direction pass the other halfwidth across the membrane. A redox cycle functions in each of the three sites of the energy coupling mechanism: the flavin (F) cycle in complex I, the Q-cycle in complex III and the O-cycle in complex IV. These cycles are interconnected by mobile carriers: the F- and Q-cycles by ubiquinone and the Q- and O-cycles by cytochrome c.

Keywords

Electron Transport, Oxygen Consumption, Ubiquinone, Animals, Cytochrome c Group, Models, Biological, Oxidation-Reduction, Mitochondria

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citations
The total number of citations received by all articles of the researcher of interest.
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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