Individualizing Care: Management Beyond Medical Therapy.
Copyright policy )Individualizing Care: Management Beyond Medical Therapy.
The evolving research landscape, with advances in the omics technologies, availability of large-scale patient cohorts, and forthcoming availability of novel drugs in primary biliary cholangitis (PBC), is creating a unique opportunity for developing a precision medicine (PM) program. PM has potential to change the paradigm of management. Diagnostic work-up of PBC patients may include information on genetic variants and molecular signature to define a particular subtype of disease and provide an estimate of treatment response and survival. To reach this point, specific interventions, such as sequencing more genomes, creating bigger biobanks, and linking biological information to health data, are needed.
- University of Milano-Bicocca Italy
- University of Cambridge United Kingdom
- University of Rome Tor Vergata Italy
- University of Milan Italy
Epigenomics, Proteomics, Liver Cirrhosis, Biliary, Gene Expression Profiling, Antineoplastic Agents, Genomics, Risk Assessment, Hepatitis, Autoimmune, Jaundice, Obstructive, Treatment Outcome, Liver, Pharmacogenetics, Neoplasms, Hypertension, Portal, Biomarkers, Tumor, Disease Progression, Autoimmune liver disease; Individualized care; Novel therapies; Omics; Precision medicine; Primary biliary cholangitis; Risk-stratification;, Elasticity Imaging Techniques, Humans, Metabolomics, Molecular Targeted Therapy, Precision Medicine, Delivery of Health Care, Liver Failure
Epigenomics, Proteomics, Liver Cirrhosis, Biliary, Gene Expression Profiling, Antineoplastic Agents, Genomics, Risk Assessment, Hepatitis, Autoimmune, Jaundice, Obstructive, Treatment Outcome, Liver, Pharmacogenetics, Neoplasms, Hypertension, Portal, Biomarkers, Tumor, Disease Progression, Autoimmune liver disease; Individualized care; Novel therapies; Omics; Precision medicine; Primary biliary cholangitis; Risk-stratification;, Elasticity Imaging Techniques, Humans, Metabolomics, Molecular Targeted Therapy, Precision Medicine, Delivery of Health Care, Liver Failure
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