Preeclampsia (PE) is a disease unique to humans. PE complicates from 3 to 14% of pregnancies worldwide. Unknown cause yet, although part of poor placentation resulting placental ischemia release of proinfammatory cytokines and anti-angiogenic factors. Two PE types: early PE with maternal and fetal adverse events and late PE with low fetal involvement and more favorable maternal-fetal prognosis. As PE predictors being considered: increased uric acid of 3.15 mg/dl as a predictor of gestational hypertension in the first quarter and greater than 5.2 mg/dl for severe/eclampsia preeclampsia. The sFLT-1/PIGF (soluble FMS-like tyrosine kinase-1/angioge nic placental growth facto) ratio is above 85 is a marker of pregnancy complications and a good indicator that helps decision making. Hypertension in pregnancy can be the beginning of vascular and metabolic alterations future; indeed the PE/eclampsia is considered a specific risk factor in women in some guides cardiovascular risk. © 2017 SEHLELHA. Published by Elsevier España, S.L.U. All rights reserved.