[Characterization of the receptor for murine gamma interferon].

F, Cofano; A, Fassio; L, Fava; G, Cavallo; S, Landolfo

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Article . 1987

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[Characterization of the receptor for murine gamma interferon].

descriptionPublicationkeyboard_double_arrow_right Article 01 May 1987 Italian Journal:Giornale di batteriologia, virologia ed immunologia, volume 78 (issn: 0390-5462,

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Authors: F, Cofano; A, Fassio; L, Fava; G, Cavallo; S, Landolfo;

pmid: 2951290

[Characterization of the receptor for murine gamma interferon].

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Abstract

Rabbits immunized with murine cells EL-4 expressing high number of interferon-gamma (IFN-gamma) receptors produce antibodies which inhibit the specific binding of murine 125I-IFN-gamma to the surface of target cells. Moreover to define the M.W. of the IFN-gamma receptor we have performed cross-linking experiments using 125I-IFN-gamma. The results obtained reveal that the IFN-gamma receptors has a M.W. of about 90-95.000 d.

Keywords

Molecular Weight, Receptors, Immunologic, Receptors, Interferon

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