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Alpha 2-plasmin inhibitor-plasmin complexes in synovial fluid.

Authors: R D, Inman; P C, Harpel;

Alpha 2-plasmin inhibitor-plasmin complexes in synovial fluid.

Abstract

The role of the fibrinolytic enzyme system in inflammatory joint disease has been addressed by several experimental approaches. In our study we examined synovial fluid (SF) in several different diseases for alpha 2-plasmin inhibitor-plasmin complexes by an enzyme linked immunosorbent assay (ELISA). These complexes are present in both rheumatoid and nonrheumatoid SF, with highest levels seen in septic arthritis. Thus the plasminogen system is intact in inflammatory SF, and plasmin may play a role in the local inflammatory process.

Keywords

Arthritis, Infectious, Complement Inactivator Proteins, alpha-2-Antiplasmin, Enzyme-Linked Immunosorbent Assay, Antifibrinolytic Agents, Arthritis, Rheumatoid, Complement C1, Synovial Fluid, Humans, Fibrinolysin

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Powered by OpenAIRE graph
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
26
Average
Top 10%
Average
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