Two patients have been described in which a calcifying odontogenic cyst has been removed. One patient concerned a 14-year-old girl with an impacted 24, in which a calcifying odontogenic cyst was removed in connection with a complex odontoma. The other patient concerned a 85-year-old man with a large cyst in the edentulous maxilla, which was marsupialized. This second patient is probably the oldest one reported in the literature concerning calcifying odontogenic cysts. Because of the age of the patient and his general condition, it was felt justified to just marsupialize the lesion instead of a more radical removal. The follow-up findings after one year seem to confirm the justification of the chosen treatment procedure.