[Effect of ionol on carcinogenesis in the kidneys].
Copyright policy )[Effect of ionol on carcinogenesis in the kidneys].
The effect of treatment with an antioxidant--ionol (2,6-di-tert-butyl, 4-methylphenol)--on nitrosodimethylamine-induced carcinogenesis was studied. Large doses of ionol were found to inhibit tumor development in the kidney. This also involved intensification of spontaneous peroxidation of renal cortical membrane cell lipids which in turn was inhibited when additional stimulation with iron was carried out.
Kidney Cortex, Time Factors, Drug Evaluation, Preclinical, Butylated Hydroxytoluene, Kidney, Kidney Neoplasms, Dimethylnitrosamine, Rats, Malondialdehyde, Animals, Lipid Peroxidation, Phospholipids
Kidney Cortex, Time Factors, Drug Evaluation, Preclinical, Butylated Hydroxytoluene, Kidney, Kidney Neoplasms, Dimethylnitrosamine, Rats, Malondialdehyde, Animals, Lipid Peroxidation, Phospholipids
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