Antihistamines and driving safety.
Copyright policy Antihistamines and driving safety.
The results of two placebo-controlled driving performance studies confirm laboratory data showing that the nonsedating antihistamine terfenadine does not influence the driving performance of users. The amplitude of vehicle weaving calculated for drivers who received this agent did not differ from control values. Neither terfenadine nor loratadine, another nonsedating antihistamine, potentiated the adverse effects of alcohol on driving performance.
- Transnational University Limburg Netherlands
Male, Automobile Driving, Ethanol, Cyproheptadine, Loratadine, Double-Blind Method, Histamine H1 Antagonists, Humans, Sleep Stages, Terfenadine, Benzhydryl Compounds, Psychomotor Performance
Male, Automobile Driving, Ethanol, Cyproheptadine, Loratadine, Double-Blind Method, Histamine H1 Antagonists, Humans, Sleep Stages, Terfenadine, Benzhydryl Compounds, Psychomotor Performance
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