In Switzerland over 20000 people die each year from an atherosclerosis derived cardiovascular disease accounting for 37 of all deaths. Mortality is highest in the first hour after a heart attack. It is therefore important to have efficient first line treatments in the emergency vehicle. Currently an injection of the vasodilator nitroglycerine acts on the entire vasculature which can lead to a dangerous drop in blood pressure without treating the diseased stenosed vessel responsible for a heart attack or stroke. A preferential release of a vasodilator at the site of a stenosis would greatly improve both the acute treatment by a selective vasodilatation and the subsequent quality of life of the patient.