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Characterization of the filarial genome.

Authors: B K, Sim; J, Shah; D F, Wirth; W F, Piessens;

Characterization of the filarial genome.

Abstract

Filarial parasites are just beginning to be studied at the genetic level. The potential of recombinant DNA technology for identifying parasite genes that are important in the pathogenesis of filarial disease or for the survival of the parasite is enormous. Work in several laboratories has already identified genes which encode ribosomal RNAs, as well as highly repeated DNA sequences that can be used as diagnostic probes. In addition, new methods to separate chromosomes will allow the physical mapping of parasite genes without the requirement for classical genetic analysis, which would be difficult in filariids.

Keywords

Electrophoresis, Agar Gel, Male, Chromosome Mapping, Nucleic Acid Hybridization, DNA, DNA Restriction Enzymes, DNA, Ribosomal, Culicidae, Genes, RNA, Ribosomal, Brugia, Animals, Female, Filarioidea, Repetitive Sequences, Nucleic Acid

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Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
6
Average
Top 10%
Average
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