Glyburide action in cultured 3T3-L1 adipocytes.
Copyright policy )Glyburide action in cultured 3T3-L1 adipocytes.
During adipocyte differentiation of 3T3-L1 cells, glyburide increased the specific activity (mU/mg protein) of glycerol-3-P dehydrogenase (by at least 14-fold) and glutamine synthetase (by 5-fold). The glyburide-mediated increases in enzyme activities were greater in the presence than in the absence of insulin. Our data indicate that glyburide either potentiates or mimics the actions of insulin to increase the activity of glycerol-3-P dehydrogenase during adipocyte differentiation of cultured 3T3-L1 cells.
Cell Differentiation, Glycerolphosphate Dehydrogenase, Glucosephosphate Dehydrogenase, Kinetics, Mice, Adipose Tissue, Glutamate-Ammonia Ligase, Glyburide, Animals, Insulin, Cells, Cultured
Cell Differentiation, Glycerolphosphate Dehydrogenase, Glucosephosphate Dehydrogenase, Kinetics, Mice, Adipose Tissue, Glutamate-Ammonia Ligase, Glyburide, Animals, Insulin, Cells, Cultured
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).3 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!