Natural variability of respiratory-syncytial viruses, their interference and reproduction characteristics.

T J, Yurlova; , Zoshchenkova NYa; L S, Karpova

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Acta Virologicaarrow_drop_down

Acta Virologica

Article . 1985

Data sources: Europe PubMed Central

Natural variability of respiratory-syncytial viruses, their interference and reproduction characteristics.

descriptionPublicationkeyboard_double_arrow_right Article 05 Nov 1985 English Journal:Acta virologica, volume 29 (issn: 0001-723X,

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Authors: T J, Yurlova; , Zoshchenkova NYa; L S, Karpova;

pmid: 2864830

Natural variability of respiratory-syncytial viruses, their interference and reproduction characteristics.

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Abstract

Over a 5-year observation period in a children-institution community, the severity of respiratory-syncytial (RS) virus infection varied within a broad range depending on biological properties of the circulating virus population. The type of virus population was characterized by a complex of biological features, namely, the extent of their reproduction and interference in tissue cultures of different origin at optimal incubation temperature. The dynamics of genetic alterations in respect to these properties within 1976-1980 was established. Moreover, the seasonal variability of the strains with respect to these properties has been determined.

Keywords

DNA Replication, Genetic Variation, Virus Replication, Respirovirus Infections, Vesicular stomatitis Indiana virus, Cell Line, Respiratory Syncytial Viruses, Trachea, Organ Culture Techniques, Humans, Child, Lung, HeLa Cells

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