
Liver specimen morphology and clinical course of a case of cholesterol ester storage disease are presented. In a 16-year-old boy on the first biopsy a massive storage of neutral fats was found light microscopically and of cholesterol ester micropolariscopically. Advanced portal field fibrosis and severe reactive hepatitis indicate the danger of progression up to metaplasia. Typical membrane-surrounded lipid inclusions were found electron microscopically in hepatic cells, stellate cells and also in bile duct epithelium.
Inclusion Bodies, Male, Microscopy, Electron, Adolescent, Cholesterol Ester Storage Disease, Liver, Liver Function Tests, Biopsy, Needle, Humans, Cholesterol Esters
Inclusion Bodies, Male, Microscopy, Electron, Adolescent, Cholesterol Ester Storage Disease, Liver, Liver Function Tests, Biopsy, Needle, Humans, Cholesterol Esters
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