[Potential value of eicosapentaenoic acid].
Copyright policy )[Potential value of eicosapentaenoic acid].
The arachidonic acid substitution by an alternative fatty acid, substrate for the 5-lipoxygenase and the cyclo-oxygenase pathway constitutes a novel therapeutic approach or a complement for other therapeutics in the inflammation area. Eicosapentaenoic acid (EPA), one of the fish oil components, is a substrate for both enzymes and an inhibitor for several enzymes of arachidonic acid cascade, in vitro and in vivo. The EPA-generated metabolites have less pro-inflammatory effects than those produced by arachidonic acid metabolism.
Arthritis, Rheumatoid, Inflammation, Arachidonate 5-Lipoxygenase, Fish Oils, Eicosapentaenoic Acid, Neutrophils, Humans, Leukotriene B4
Arthritis, Rheumatoid, Inflammation, Arachidonate 5-Lipoxygenase, Fish Oils, Eicosapentaenoic Acid, Neutrophils, Humans, Leukotriene B4
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).0 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!