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Antimicrobial consumption and antimicrobial resistance: a snapshot of an Italian neuromuscular rehabilitation center.

Authors: Barberi, Giuseppina; De Cola, Maria Cristina; Dell'Utri, De Cola; Melardi, Sara; Alagna, Bernardo; Bramanti, Placido; Cascio, Antonio;

Antimicrobial consumption and antimicrobial resistance: a snapshot of an Italian neuromuscular rehabilitation center.

Abstract

The paper presents a snapshot of the incidence of antimicrobial-resistant microorganisms and antimicrobial consumption in an Italian rehabilitation center over a two-year period (2014-2015). Data on microorganism identification and antimicrobial susceptibility testing were obtained from the diagnostic laboratory of the hospital. A set of indicators was assessed, including the incidence density of resistant isolates per 1000 patient-days (IDRI). Data on antimicrobial consumption, semi-annually, obtained from the hospital pharmacy, were expressed as Defined Daily Dose (DDD) per 1000 patient-days. The most frequently isolated microorganism was Klebsiella pneumoniae (19.3%), and a significant increase in piperacillin/tazobactam- resistant K. pneumoniae (p=0.04) was observed. Among all antimicrobials used, carbapenems were the most prescribed antibiotic class (31%).

Country
Italy
Keywords

Microbiology (medical), Catheters, Settore MED/17 - Malattie Infettive, Bacteria, Antimicrobial consumption; Antimicrobial resistance; DDD per 1000 patient-days; Healthcare-associated infections; Rehabilitation hospital; Anti-Bacterial Agents; Bacteria; Catheters; Drug Utilization; Intubation, Gastrointestinal; Italy; Neuromuscular Diseases; Risk Factors; Drug Resistance, Bacterial; Rehabilitation Centers, Healthcare-Associated infections, Neuromuscular Diseases, Antimicrobial resistance, Rehabilitation hospital, DDD per 1000 patient-days, Rehabilitation Centers, Drug Utilization, Anti-Bacterial Agents, Italy, Risk Factors, Antimicrobial consumption, Drug Resistance, Bacterial, Antimicrobial consumption; Antimicrobial resistance; DDD per 1000 patient-days; Healthcare-Associated infections.; Rehabilitation hospital; Microbiology (medical), Intubation, Gastrointestinal

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
Green