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The normal human optic nerve. Axon count and axon diameter distribution.

Authors: F S, Mikelberg; S M, Drance; M, Schulzer; H M, Yidegiligne; M M, Weis;

The normal human optic nerve. Axon count and axon diameter distribution.

Abstract

Computerized image analysis was used to determine the normal axonal count and axon diameter distribution in 12 normal human eyes. Mean axon count per nerve was 969,279 +/- 239,740 and mean axon diameter was 0.72 +/- 0.07 micron. Multiple linear regression disclosed 4909 axons lost yearly (P = 0.08). Statistical analysis did not show a relationship between axon diameter and age or time to fixation. The inferotemporal sector of the nerve had the highest fiber density (P = 0.02). The superonasal nerve had higher mean diameters (P = 0.02). This study may provide a baseline for future pathologic studies.

Related Organizations
Keywords

Adult, Electronic Data Processing, Adolescent, Infant, Cell Count, Optic Nerve, Middle Aged, Eye, Axons, Reference Values, Child, Preschool, Humans, Child, Aged

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Powered by OpenAIRE graph
Found an issue? Give us feedback
citations
The total number of citations received by all articles of the researcher of interest.
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
246
Top 1%
Top 1%
Top 10%
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