
Iontophoretic currents (0--1.0 mA) were applied to dentin disks prepared from human third molars. A negative electrode increased 125I-permeation 10X, while a positive electrode increased 14C-lidocaine 8X. Iontophoresis appears promising as a method to increase the permeation of dentin by ionized substances of therapeutic interest.
Dentin Permeability, Diffusion, Iodine Radioisotopes, Tooth Permeability, Dentin, Humans, Lidocaine, Carbon Radioisotopes, Iontophoresis
Dentin Permeability, Diffusion, Iodine Radioisotopes, Tooth Permeability, Dentin, Humans, Lidocaine, Carbon Radioisotopes, Iontophoresis
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