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[Necrotizing funisitis : Histopathological indicator of occult congenital syphilis].

Authors: K, Hussein; C, Peter; L, Sedlacek; C von, Kaisenberg; H H, Kreipe;

[Necrotizing funisitis : Histopathological indicator of occult congenital syphilis].

Abstract

Congenital syphilis is a rare disease in central Europe. Placental changes may be non-specific but a typical finding is necrotizing funisitis of the umbilical cord. In a case report we describe how the histopathological incidental finding of B lymphocyte-rich, necrotizing funisitis led to the diagnosis of a previously unknown Treponema pallidum infection in parents and their newborn child. The pathological suspicion of congenital syphilis, although rare, has implications for the clinical management (serological evaluation of parents and child as well as the social environment, evaluation of viral coinfection and treatment decision) and is a notifiable disease.

Keywords

Male, B-Lymphocytes, Delayed Diagnosis, Fetal Growth Retardation, Cesarean Section, Placenta, Pregnancy Trimester, Third, Syphilis, Congenital, T-Lymphocytes, Infant, Newborn, Infant, Infant, Premature, Diseases, Syphilis Serodiagnosis, Umbilical Cord, Necrosis, Young Adult, Chorioamnionitis, Pregnancy, Humans, Female

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
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