Anti-inflammatory Prenylated Flavonoids from Helminthostachys zeylanica.
Copyright policy )Anti-inflammatory Prenylated Flavonoids from Helminthostachys zeylanica.
Two new [neougonins A (1) and B (2)] and nine known prenylated flavonoids were isolated from the whole plants of Helminthostachys zeylanica. The structures of the new isolates were elucidated by extensive NMR techniques, including one and two dimensional (1D)- and (2D)-NMR experiments, as well as comparison with spectroscopic data of known analogous compounds. Moreover, compound 1 inhibited lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cells with an IC50 value of 3.32 µM.
- Kunming University of Science and Technology China (People's Republic of)
Flavonoids, Lipopolysaccharides, Prenylation, Dose-Response Relationship, Drug, Molecular Structure, Macrophages, Anti-Inflammatory Agents, Non-Steroidal, Nitric Oxide, Mice, Structure-Activity Relationship, Ferns, Animals
Flavonoids, Lipopolysaccharides, Prenylation, Dose-Response Relationship, Drug, Molecular Structure, Macrophages, Anti-Inflammatory Agents, Non-Steroidal, Nitric Oxide, Mice, Structure-Activity Relationship, Ferns, Animals
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