[TAFRO syndrome and monoclonal gammapathy: Uncommon association!].

M, Naifar; M, Messedi; A, Elleuch; M, Snoussi; N, Gouiaa; M, Turki; A, Lahiani; T, Boudawara; Z, Bahloul; F, Ayedi

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Current Research in Translational Medicine

Article . 2018

Data sources: Europe PubMed Central

[TAFRO syndrome and monoclonal gammapathy: Uncommon association!].

descriptionPublicationkeyboard_double_arrow_right Article 05 Apr 2018 French Journal:Current research in translational medicine, volume 64 (issn: 2452-3186,

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Authors: M, Naifar; M, Messedi; A, Elleuch; M, Snoussi; N, Gouiaa; M, Turki; A, Lahiani; +3 Authors

pmid: 27140598

[TAFRO syndrome and monoclonal gammapathy: Uncommon association!].

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Abstract

Castleman's disease is a lymphoproliferative disorder characterized by angiofollicular lymph node hyperplasia. Recently, a new variant of multicentric Castleman's disease has been identified in Japan called TAFRO syndrome. It is characterized by a constellation of symptoms: thrombocytopenia, anasarca, reticulin fibrosis of the bone marrow, renal dysfunction and organomegaly (TAFRO). It is usually associated with polyclonal hyperimmunoglobulinemia. Here, we report the first and unique case of TAFRO syndrome with monoclonal gammapathy.

Keywords

Male, Fever, Castleman Disease, Syndrome, Middle Aged, Blood Protein Electrophoresis, Monoclonal Gammopathy of Undetermined Significance, Immunoglobulin kappa-Chains, Immunoglobulin G, Splenomegaly, Humans, Lymph Nodes, Rituximab, Immunosuppressive Agents, Hepatomegaly

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