To date, there has been no report of coinfection of human WU polyomavirus (WUPyV) with norovirus (NV). WUPyV has been detected in stool indicating pathogenicity of the gastrointestinal tract. Feces from 110 children (58 males, 52 females) with acute gastroenteritis admitted to Wei-Gong Memorial Hospital, Taiwan were screened for the presence of WUPyV and NV GII by PCR and RT-qPCR, respectively revealing three males with WUPyV only and one male with both viruses, the latter being first such report. There are no significant differences in clinical symptoms between patients with and without viral infection. Phylogenetic analysis based on WUPyV VP2 sequences indicated that the four samples are closely related to strains epidemic in China.