
The liver performs a vital role in metabolism, secretion, storage, and detoxification of endogenous and exogenous substances. Oxidative stress and free radicals enhance the severity of hepatic damage, which can be overcome by the antioxidant mechanism. Plant extracts can be the best source of such antioxidants and mediate hepatoprotective activity. In this chapter, high-dose paracetamol-induced hepatotoxicity in rat model is discussed with explanations of biochemical and histopathological studies.
Bioprospecting, Male, Plants, Medicinal, Plant Extracts, Phytochemicals, Antioxidants, Disease Models, Animal, Oxidative Stress, Liver, Cytoprotection, Drug Discovery, Animals, Female, Chemical and Drug Induced Liver Injury, Rats, Wistar, Acetaminophen, Phytotherapy
Bioprospecting, Male, Plants, Medicinal, Plant Extracts, Phytochemicals, Antioxidants, Disease Models, Animal, Oxidative Stress, Liver, Cytoprotection, Drug Discovery, Animals, Female, Chemical and Drug Induced Liver Injury, Rats, Wistar, Acetaminophen, Phytotherapy
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 0 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
