Scaling and subgingival curettage were performed on the upper and lower front teeth of 25 patients in the age of 25 to 35 years. Peripac was applied to the periodontal tissue of three of the six teeth treated per subject and Histoacryl to the periodontal tissue of the other three teeth. Prior to and three months after the beginning of therapy, pocket depth, sulcus bleeding tooth mobility were determined. It was found that the use of Histoacryl as a dressing material is not a disadvantage as compared to the conventional dressing Peripac as far as therapeutic success in terms of declining pocket depth and SBI is concerned.