The success of root canal treatment is determined by satisfying the basic principles of complete removal of the endodontic pathology through chemo-mechanical cleansing of the root canals followed by shaping and then by obturation to provide the ideal hermetic seal. To achieve such success a thorough knowledge of the root canal anatomy is a basic requirement. Several anatomic variations of the mandibular molars have been reported among which is the reportedly rare Radix Entomolaris(RE), a mandibular molar with an additional root located lingually.To present five cases of RE diagnosed pre-operatively using radiographs and subsequently successfully endodontically treated. We also aim to highlight the considerations for the diagnosis and management of RE in general dental practice.Even though RE is rarely encountered in general dental practice, the possibility that it may occur warrants the need to have sufficient knowledge regarding diagnosis and the appropriate modifications in endodontic management of these teeth. Preparedness coupled with a carefully modified clinical approach aids in successful management of RE and ensures that these cases could be handled with ease.