Individual phenotypes, phenotypical and genetic frequencies of the alpha-amylase enzyme have been established by means of populational genetic researches. The most common phenotype is AmylA Amyl2A (85.15%) followed by AmylA Amyl2A 2B (6.27%), AmylAIB Amyl2A (5.37%), Amyl IA Amyl2A 2B (2.15%), AmylA Amyl2B (0.53%), AmylC Amyl2B (0.35%), AmylC Amyl2A 2B (0.18%). The difference between the observed and theoretically expected phenotypes of Amy, Hp and M Gm(1) is insignificant. The examined contingent from the Bulgarian population is found to be in genetic balance. Statistical analysis of the reuö results does not prove a genetic link between Amy, Hp and Gm (1).