
pmid: 25720699
handle: 20.500.12491/8535
Dear Editor, We thank to the authors for their valuable comments about our study1. They emphasized that elevated red cell distribution width (RDW) helps to early diagnosis of nutritional deficiency of iron, folic acid and vitamin B12. Also they pointed to elevated RDW could be associated with sickle cell anemia, hemolytic anemia, chronic liver disease and myelodysplastic syndrome. Possible causes of high RDW levels can be determined by comparison with mean corpuscular volume (MCV). The MCV is the average amount of space occupied by each red blood cell. If both the RDW and MCV levels are increased, there are several possible causes such as liver disease, hemolytic anemia and vitamin B12 or folic acid deficiency. Another condition is the combination of high RDW levels with low MCV levels. This may be resulted from iron deficiency anemia or thalessemia intermedia. In our study, the patient groups did not have nutritional anemias according to their MCV levels were in normal range for their age groups (6 months up to 6 years old)2. Also, due to retrospective nature of our study, it is not possible to investigate ferritin, folic acid and vitamin B12 levels of the patients.
Male, Erythrocytes, Vitamin B12, Neutrophils, MCV Levels, Seizures, Febrile, Red Cell Distribution Width, Red Cell, RDW, Humans, Female, Lymphocytes
Male, Erythrocytes, Vitamin B12, Neutrophils, MCV Levels, Seizures, Febrile, Red Cell Distribution Width, Red Cell, RDW, Humans, Female, Lymphocytes
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