To isolate and elucidate the constituents from whole plant of Pholidota cantonensis.The constituents were isolated and purified by silica gel, Sephadex LH-20 and MCI gel chromatography and recrystallization. The structures were elucida- ted on the basis of the chemical evidence and spectroscopic data.Ten compounds were obtained : batatasin ll(1), orchinol(2), ephmeranthoquinone(3 ), densiflorol B (4) , 3, 5-dimethoxy-4-hydroxy-propiophenone (5) , cinnamic acid (6) , syringaresinol (7) ,24- methylenencycoartanol( 8),ergosterol peroxide(9) and β-sitosterol( 10).Compounds 6 and 9 are isolated from Pholidota genus for the first time,and compounds 4,5 and 7 are isolated from this plant for the first time.