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Hiroshima University Institutional Repository
Research . 1989
Data sources: Hiroshima University Institutional Repository
https://pubmed.ncbi.nlm.nih.go...
Article . 1989
Data sources: Europe PubMed Central
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Nephrotoxicity of pyrroloquinoline quinone in rats.

descriptionPublicationkeyboard_double_arrow_right Article , Research , Report 01 Mar 1989 Japan English Publisher:Hiroshima University Medical PressJournal:Hiroshima journal of medical sciences, volume 38 (issn: 0018-2052, Copyright policy )
Authors: Watanabe, Akiharu; Hobara, Norio; Ohsawa, Toshiya; Higashi, Toshihiro; Tsuji, Takao;

pmid: 2546903

Nephrotoxicity of pyrroloquinoline quinone in rats.

Abstract

When pyrroloquinoline quinone (PQQ) was intraperitoneally injected into rats daily for 4 days at a dose of 11.5 mg/kg body weight/injection, functional and morphologic changes of the kidneys were clearly observed. The most prominent finding was necrotic and degenerative changes of the proximal tubular epithelium as well as hematuria and an elevation of serum creatinine concentration.

Country
Japan
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Keywords

Male, 490, PQQ Cofactor, 610, Rats, Inbred Strains, Quinolones, Kidney, 620, Rats, Creatinine, Pyrroloquinoline quinone, Animals, Nephrotoxicity, Renal tubules

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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