The management of peripheral arterial disease (PAD) has drastically changed since the introduction and advancement of endovascular surgery. The majority of PAD that requires mechanical treatment is managed with endovascular interventions using a variety of techniques and devices. The infrainguinal vasculature, especially the superficial femoral artery (SFA), poses a significant challenge to successful long-term outcomes for a variety of reasons. Because some of these procedures have limited longevity, the management of patients that require reintervention is worthy of special consideration and strategic discussion. This article reviews the risks and failure modes of SFA interventions and the treatment options and techniques for reinterventions.