[A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders].

V E, Medvedev; O N, Tereshchenko; A Iu, Israelian; I K, Chobanu; N V, Kost; O Iu, Sokolov; N F, Miasoedov

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Zhurnal nevrologii i psikhiatrii im S S Korsakova

Article . 2014

Data sources: Europe PubMed Central

[A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders].

descriptionPublicationkeyboard_double_arrow_right Article 19 Dec 2014 Russian Journal:Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, volume 114 (issn: 1997-7298,

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Authors: V E, Medvedev; O N, Tereshchenko; A Iu, Israelian; I K, Chobanu; N V, Kost; O Iu, Sokolov; N F, Miasoedov;

pmid: 25176261

[A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders].

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Abstract

Objective. To study the efficacy and tolerability of the new anxyolytic peptide selank in comparison with phenazepam. Material and methods. A comparative study of the anxiolytic effect and tolerability of selank and phenazepam was carried out in 60 patients with phobic-anxiety- and somatoform disorders (F40.2-9, F41.1-9, F45.0-1 by ICD-10) were examined. Results Pronounced anxiolytic and mild nootropic effects of selank were demonstrated. The anxiolytic effect lasted for a week after last receiving the peptide. Selank had a positive impact on the quality of life of the patients. Conclusion. The data obtained in the study extend therapeutic possibilities in the treatment of anxiety disorders.

Keywords

Adult, Male, Adolescent, Middle Aged, Anxiety Disorders, Benzodiazepines, Young Adult, Anti-Anxiety Agents, Humans, Female, Oligopeptides

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